Protein Smoothened

**Semantic type:** Amino Acid, Peptide, or Protein|Receptor

**Definition:** Protein smoothened (787 aa, ~86 kDa) is encoded by the human SMO gene. This protein plays a role in the modulation of hedgehog signaling pathways.

**Synonyms:** - Gx Protein - Protein Gx - SMO - SMOH - Smoothened - Smoothened Homolog - Smoothened Homolog