C18106Level 5
Receptor
**Semantic type:** Amino Acid, Peptide, or Protein|Receptor
**Definition:** A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.
**Synonyms:** - Receptor Protein - receptor
GET
/api/v1/systems/nci_thesaurus/nodes/C18106Hierarchy Explorer
Hierarchy Explorer
Cross-system equivalences0
No cross-system equivalences mapped for this node.