ALVAC-CEA (6D)-B7.1 Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-CEA (6D)-B7.1 vaccine expresses both a highly immunogenic analogue (6D) of the immunodominant epitope of carcinoembryonic antigen (CEA) and B7.1 (also known as CD80), the natural ligand for the T-cell antigen CD28. This agent was designed to stimulate host immune responses against tumor cells that express CEA. (NCI04)

**Synonyms:** - ALVAC-CEA (6D)-B7.1