E3 Ubiquitin-Protein Ligase RNF139

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase RNF139 (664 aa, ~76 kDa) is encoded by the human RNF139 gene. This protein plays a role in protein ubiquitination, inhibition of cell proliferation and cell cycle regulation.

**Synonyms:** - EC 2.3.2.27 - EC 6.3.2.-, Formerly - Multiple Membrane Spanning Receptor TRC8 - Patched Related Protein TRC8 - RNF139 - Ring Finger 139 - TRC8 - Translocation In Renal Carcinoma On Chromosome 8 Protein