Oligodendroglioma

**Semantic type:** Neoplastic Process

**Definition:** A well-differentiated (WHO grade 2), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO)

**Synonyms:** - Oligodendroglioma, NOS - WHO Grade 2 Oligodendroglial Neoplasm - WHO Grade 2 Oligodendroglial Tumor - WHO Grade II Oligodendroglial Neoplasm - WHO Grade II Oligodendroglial Tumor - Well Differentiated Oligodendroglial Tumor - Well Differentiated Oligodendroglioma - oligodendroglioma