Acute Promyelocytic Leukemia with t(11;17)(q23;q21); ZBTB16-RARA

**Semantic type:** Neoplastic Process

**Definition:** Acute promyelocytic leukemia with a variant RARA rearrangement associated with t(11;17)(q23;q21) that results in the expression of ZBTB16-RARA fusion protein. It lacks differentiation response to retinoids treatment.

**Synonyms:** - APL with t(11;17)(q23;q21); PLZF-RARA - APL with t(11;17)(q23;q21); ZBTB16-RARA - Acute Myeloid Leukemia with t(11;17)(q23;q21) - Acute Myeloid Leukemia with t(11;17)(q23;q21) - Acute Myeloid Leukemia with t(11;17)(q23;q21); ZBTB16-RARA - Acute Myeloid Leukemia with t(11;17)(q23;q21); ZBTB16-RARA Fusion - Acute Myeloid Leukemia with t(11;17)(q23;q21); ZBTB16::RARA - Acute Myeloid Leukemia with t(11;17)(q23;q21); ZBTB16::RARA Fusion - Acute Promyelocytic Leukemia with t(11;17)(q23;q21); PLZF-RARA - Acute Promyelocytic Leukemia with t(11;17)(q23;q21); PLZF-RARA - Acute Promyelocytic Leukemia with t(11;17)(q23;q21); ZBTB16::RARA