BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant inherited syndrome caused by deleterious mutations in the BRCA1 gene. Affected individuals are at high risk of developing breast cancer, ovarian cancer, and other cancers including cervical, endometrial, fallopian tube, and colon cancer.

**Synonyms:** - BRCA1 Syndrome - BRCA1 Syndrome - BRCA1 Syndrome - BRCA1-Associated Hereditary Breast and Ovarian Cancer Syndrome - BROVCA1 - Early Onset Breast Ovarian Cancer Syndrome