BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant inherited syndrome caused by deleterious mutations in the BRCA2 gene. Affected individuals are at high risk of developing female and male breast cancer, ovarian cancer, and other cancers including prostatic cancer, pancreatic cancer, gastric cancer, and melanoma.

**Synonyms:** - BRCA2 Syndrome - BRCA2 Syndrome - BRCA2 Syndrome - BRCA2-Associated Hereditary Breast and Ovarian Cancer Syndrome - BROVCA2 - Site Specific Early Onset Breast Cancer Syndrome