RB1 Gene Inactivation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A mutation in the RB1 gene that either inhibits expression of the RB1 protein or results in the translation of an inactive RB1 protein.

**Synonyms:** - Inactivating RB Gene Mutation - Inactivating RB1 Gene Mutation - Inactivating Retinoblastoma 1 Gene Mutation - Inactivating Retinoblastoma Gene Mutation - Inactivation of Retinoblastoma Tumor-Suppressor Gene - Loss of Function RB1 Gene Mutation - Loss of Function RB1 Mutation - RB1 Loss of Function Gene Mutation - RB1 Loss of Function Mutation - RB1 Tumor-Suppressor Gene Inactivation