Inactivating IGF2R Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the IGF2R gene that either inhibits expression or results in the translation of an inactive cation-independent mannose-6-phosphate receptor protein.

**Synonyms:** - IGF2R Gene Inactivation - IGF2R Tumor-Suppressor Gene Inactivation - Inactivating CD222 Gene Mutation - Inactivating CIMPR Gene Mutation - Inactivating IGF2R Mutation - Inactivating Insulin Like Growth Factor 2 Receptor Gene Mutation - Inactivating Insulin-Like Growth Factor 2 Receptor Gene Mutation - Inactivating MPR1 Gene Mutation - Inactivating MPRI Gene Mutation - Loss of Function IGF2R Gene Mutation - Loss of Function IGF2R Mutation