Inactivating APC Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the APC gene that either inhibits expression or results in the translation of an inactive adenomatosis polyposis coli protein.

**Synonyms:** - APC Gene Inactivation - APC Inactivating Gene Mutation - APC Inactivating Mutation - APC Loss of Function Gene Mutation - APC Loss of Function Mutation - APC Loss of Function Mutation - APC Tumor-Suppressor Gene Inactivation - Inactivating APC Mutation - Inactivating APC, WNT Signaling Pathway Regulator Gene Mutation - Inactivating Adenomatosis Polyposis Gene Mutation - Inactivating BTPS2 Gene Mutation - Inactivating FAP Gene Mutation - Inactivating FPC Gene Mutation - Inactivating PPP1R46 Gene Mutation