Inactivating VHL Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the VHL gene that either inhibits expression or results in the translation of an inactive von Hippel-Lindau disease tumor suppressor protein.

**Synonyms:** - Inactivating VHL Mutation - Inactivating VHL1 Gene Mutation - Inactivating Von Hippel Lindau Tumor Suppressor Gene Mutation - Loss of Function VHL Gene Mutation - Loss of Function VHL Mutation - Loss of Function Von Hippel-Lindau Tumor Suppressor Gene Mutation - VHL Gene Inactivation - VHL Tumor-Suppressor Gene Inactivation