TSC2 Gene Inactivation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A mutation in the TSC2 gene that either inhibits the expression of or results in the translation of an inactive tuberin protein.

**Synonyms:** - Inactivating TSC2 Gene Mutation - TSC2 Tumor-Suppressor Gene Inactivation - Tuberin Gene Inactivation - Tuberous Sclerosis 2 Gene Inactivation