Inactivating FHIT Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the FHIT gene that either inhibits expression or results in the translation of an inactive bis(5'-adenosyl)-triphosphatase protein.

**Synonyms:** - FHIT Gene Inactivation - FHIT Tumor-Suppressor Gene Inactivation - Inactivating AP3Aase Gene Mutation - Inactivating FHIT Mutation - Inactivating FRA3B Gene Mutation - Inactivating Fragile Histidine Triad Diadenosine Triphosphatase Gene Mutation - Inactivating Fragile Histidine Triad Gene Mutation - Loss of Function FHIT Gene Mutation - Loss of Function FHIT Mutation