Signet Ring Cell Adenocarcinoma

**Semantic type:** Neoplastic Process

**Definition:** A usually aggressive, poorly differentiated invasive adenocarcinoma characterized by the presence of malignant glandular cells in which the nucleus is pressed to one side by the presence of intracytoplasmic mucus. It may arise from the stomach, small and large intestine, ampulla of Vater, appendix, gallbladder, pancreas, lung, bladder, breast, and prostate gland.

**Synonyms:** - Signet Ring Cell Carcinoma - Signet Ring Cell Carcinoma - Signet ring cell adenocarcinoma - Signet ring cell carcinoma - Signet-Ring Cell Carcinoma - signet ring cell carcinoma