Colorectal Signet Ring Cell Adenocarcinoma

**Semantic type:** Neoplastic Process

**Definition:** An invasive colorectal adenocarcinoma characterized by the presence of malignant glandular epithelial cells with prominent intracytoplasmic mucin resulting in the displacement of the nuclei. The malignant glandular cells with intracytoplasmic mucin constitute more than 50% of the malignant cellular infiltrate.

**Synonyms:** - Colorectal Signet Ring Cell Carcinoma - Colorectal Signet-Ring Cell Carcinoma