TSC1 Gene Inactivation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A mutation in the TSC1 gene that either inhibits the expression of or results in the translation of an inactive hamartin protein.

**Synonyms:** - Hamartin Gene Inactivation - Inactivating TSC1 Gene Mutation - Inactivating TSC1 Mutation - Loss of Function TSC1 Mutation - TSC Gene Inactivation - TSC1 Inactivating Mutation - TSC1 Loss of Function Gene Mutation - TSC1 Loss of Function Mutation - TSC1 Tumor-Suppressor Gene Inactivation - Tuberous Sclerosis 1 Gene Inactivation