Anaplastic Ependymoma

**Semantic type:** Neoplastic Process

**Definition:** A WHO grade 3 malignant glioma of ependymal origin with accelerated growth and an unfavorable clinical outcome, particularly in children. It is characterized by high mitotic activity, often accompanied by microvascular proliferation and pseudo-palisading necrosis. (Adapted from WHO)

**Synonyms:** - Anaplastic Ependymal Neoplasm - Anaplastic Ependymal Tumor - Ependymoma with Anaplasia - Ependymoma, anaplastic - Malignant Ependymoma - Undifferentiated Ependymal Neoplasm - Undifferentiated Ependymal Tumor - Undifferentiated Ependymoma - WHO Grade 3 Ependymal Neoplasm - WHO Grade 3 Ependymal Tumor - WHO Grade III Ependymal Neoplasm - WHO Grade III Ependymal Tumor