Inactivating CDK4 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the CDK4 gene that either inhibits expression or results in the translation of an inactive cyclin-dependent kinase 4 protein.

**Synonyms:** - CDK4 Gene Inactivation - Inactivating CDK4 Mutation - Inactivating Cell Division Kinase 4 Gene Mutation - Inactivating Cyclin Dependent Kinase 4 Gene Mutation - Loss of Function CDK4 Gene Mutation - Loss of Function CDK4 Mutation