Ras-Specific Guanine Nucleotide-Releasing Factor 2

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Ras-specific guanine nucleotide-releasing factor 2 (1273 aa, ~141 kDa) is encoded by the human RASGRF2 gene. This protein is involved in calcium-regulated nucleotide exchange factor actity that activates both Ras proteins and Ras-related C3 botulinum toxin substrate 1.

**Synonyms:** - GRF2 - RASGRF2 - Ras Guanine Nucleotide Exchange Factor 2 - Ras Protein Specific Guanine Nucleotide Releasing Factor 2 - Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 - Ras-GRF2