C4323Level 10
Pleomorphic Xanthoastrocytoma
**Semantic type:** Neoplastic Process
**Definition:** A WHO grade 2 astrocytic tumor with a relatively favorable prognosis. It is characterized by pleomorphic and lipidized cells expressing GFAP often surrounded by a reticulin network and eosinophilic granular bodies. It presents in the superficial cerebral hemispheres and involves the meninges. It typically affects children and young adults.
**Synonyms:** - PXA - Pleomorphic Xantho-Astrocytoma - Pleomorphic xanthoastrocytoma
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