Diffuse Large B-Cell Lymphoma Unclassifiable

**Semantic type:** Neoplastic Process

**Definition:** A biologic subset of diffuse large B-cell lymphomas (DLBCL) that do not overexpress the genes whose overexpression characterizes the germinal center B-cell-like and activated B-cell-like DLBCL. Morphologically, these lymphomas are either immunoblastic or centroblastic. Patients with this type of diffuse large B-cell lymphoma are reported to have a less favorable outcome, similar to those with an activated B-cell-like gene expression profile.

**Synonyms:** - DLBCL Unclassifiable - Diffuse Large B-Cell Lymphoma Indeterminate - Type 3 DLBCL - Type 3 Diffuse Large B-Cell Lymphoma