Proto-Oncogene DBL

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Proto-oncogene DBL (925 aa, ~108 kD) is encoded by the human MCF2 gene. This cytoplasmic protein promotes the conversion of certain Rho GTPases from the GDP-bound form to the GTP-bound form, thereby modulating their activity.

**Synonyms:** - MCF2 p66 Protein - Proto-Oncogene DBL Protein - Proto-Oncogene MCF-2