Paclitaxel-Loaded Polymeric Micelle

**Semantic type:** Pharmacologic Substance

**Definition:** A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer micelle nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity. Paclitaxel promotes microtubule assembly and prevents depolymerization, thus interfering with normal mitosis. The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone.

**Synonyms:** - Cynviloq TM - Genexol PM - IG-001 - paclitaxel-loaded polymeric micelle