PPP2R1B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PPP2R1B wild-type allele is located in the vicinity of 11q23.2 and is approximately 40 kb in length. This allele, which encodes serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform protein, plays a role in coordinating the assembly of the protein phosphatase 2A heterodimer. Functional PPP2R1B gene polymorphisms are associated with lung cancer.

**Synonyms:** - Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit A (PR 65), Beta Isoform wt Allele