CXCR2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CXCR2 wild-type allele is located within 2q35 and is approximately 11 kb in length. This allele, which encodes C-X-C chemokine receptor type 2 protein, is involved in the mediation of neutrophil migration to sites of inflammation, cellular growth, and angiogenic effects in intestinal microvascular endothelial cells. Allelic variants of the gene are associated with serum-dependent melanoma cell growth.

**Synonyms:** - CD182 - CDw128b - CMKAR2 - Chemokine (C-X-C Motif) Receptor 2 wt Allele - Chemokine, CXC Motif, Receptor 2 Gene - IL8R2 - IL8RB - Interleukin 8 Receptor, Beta Gene - Interleukin 8 Receptor, Type 2 Gene