TBP wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TBP wild-type allele is located in the vicinity of 6q27 and is approximately 18 kb in length. This allele, which encodes TATA-box-binding protein, is involved in the mediation of transcription. Mutations that expand the number of CAG nucleotide repeats in the gene are associated with spinocerebellar ataxia 17.

**Synonyms:** - GTF2D - GTF2D1 - SCA17 - TATA Box Binding Protein Gene - TATA Sequence-Binding Protein wt Allele - TBP