PDGFRL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PDGFRL wild-type allele is located within 8p22-p21.3 and is approximately 66 kb in length. This allele, which encodes platelet-derived growth factor receptor-like protein, plays a putative role in the inhibition of cell growth and proliferation. Loss of PDGFRL gene function is associated with several types of cancer including colorectal cancers, hepatocellular carcinomas and non-small cell lung carcinomas.

**Synonyms:** - PDGRL - PRLTS - Platelet-Derived Growth Factor Receptor-Like wt Allele