Lomefloxacin

**Semantic type:** Antibiotic|Pharmacologic Substance

**Definition:** A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis.

**Synonyms:** - LOMEFLOXACIN