Osteosarcoma Arising in Paget Disease of Bone

**Semantic type:** Neoplastic Process

**Definition:** A sarcomatous transformation of pre-existing Paget disease of the bone. Osteosarcomas arising from Paget disease of the bone are high grade lesions and usually have a poor prognosis.

**Synonyms:** - Osteosarcoma Arising in Bone Paget's Disease - Osteosarcoma Arising in Osseous Paget's Disease - Osteosarcoma Arising in Osteitis Deformans - Osteosarcoma Arising in Paget's Disease of Bone - Osteosarcoma in Paget Disease of Bone - Osteosarcoma in Paget disease of bone - Paget Osteosarcoma - Paget's Osteosarcoma