E3 Ubiquitin-Protein Ligase NEDD4

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase NEDD4 (1000 aa, ~115 kDa) is encoded by the human NEDD4 gene. This protein is involved in the transfer of ubiquitin to target proteins and may play a role in virion budding from infected cells and tumor suppression.

**Synonyms:** - Cell Proliferation-Inducing Gene 53 Protein - EC 2.3.2.26 - EC 6.3.2.-, Formerly - NEDD-4 - Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 4 - Receptor-Potentiating Factor 1