Diffuse Astrocytoma

**Semantic type:** Neoplastic Process

**Definition:** A low-grade (WHO grade 2) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified.

**Synonyms:** - ASTROCYTOMA, DIFFUSE, MALIGNANT - Astrocytoma, Diffuse - Diffuse astrocytoma - Grade 2 Astrocytic Neoplasm - Grade 2 Astrocytic Tumor - Grade 2 Astrocytoma - Grade II Astrocytic Neoplasm - Grade II Astrocytic Tumor - Grade II Astrocytoma - Low-grade astrocytoma, NOS - WHO Grade 2 Astrocytoma - WHO Grade II Astrocytoma