Bisnafide

**Semantic type:** Pharmacologic Substance

**Definition:** A bis-naphthalimide compound with anticancer activity. Bisnafide selectively intercalates guanine-cytosine (GC) rich regions of DNA, thereby interfering with DNA replication machinery and activity of topoisomerase II. As a result, this agent causes potent cytotoxicity.

**Synonyms:** - BISNAFIDE - DMP 840