Cevipabulin

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth.

**Synonyms:** - CEVIPABULIN - Cevipabulinum - TTI 237 - TTI-237 - Tubulin Binding Agent TTI-237