Thrombotic Thrombocytopenic Purpura

**Semantic type:** Disease or Syndrome

**Definition:** A coagulation disorder characterized by extensive formation of thrombi in small blood vessels throughout the body due to low levels of ADAMTS13 protein, and resulting in consumption of circulating platelets, which is characterized by thrombocytopenia, anemia, neurologic changes, and sometimes fever and renal dysfunction.

**Synonyms:** - Moschowitz Disease - TTP - TTP - Thrombotic thrombocytopenic purpura