Dinaciclib

**Semantic type:** Pharmacologic Substance

**Definition:** A pyrazolo[1,5-a]pyrimidine with potential antineoplastic activity. Dinaciclib selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9; inhibition of CDK1 and CDK2 may result in cell cycle repression and tumor cell apoptosis.

**Synonyms:** - 2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5- a]pyrimidin-5-yl]-, (2S)- - CDK Inhibitor SCH 727965 - CDK inhibitor SCH 727965 - DINACICLIB - MK 7965 - MK-7965 - MK7965 - SCH 727965 - SCH-727965 - SCH727965 - dinaciclib