World Of Taxonomy
C2185Level 6

Cyclin-Dependent Kinase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits cyclin-dependent kinase (CDK), an enzyme that catalyzes the addition of a phosphate group to a protein in the cell cycle regulation pathway. Inhibition of cyclin-dependent kinase results in cell cycle arrest and apoptosis.

**Synonyms:** - CDK Inhibitor - CDKI

GET/api/v1/systems/nci_thesaurus/nodes/C2185
Official DownloadCC BY 4.0Source