B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1

**Semantic type:** Neoplastic Process

**Definition:** A precursor lymphoid neoplasm which is composed of B lymphoblasts and carries a translocation between the TEL gene on chromosome 12 and the AML1 gene on chromosome 21, (p13.2;q22.1). It results in the production of the TEL-AML1 (ETV6-RUNX1) fusion protein. It has a favorable clinical outcome.

**Synonyms:** - B Lymphoblastic Leukemia/Lymphoma with ETV6-RUNX1 Fusion - B Lymphoblastic Leukemia/Lymphoma with ETV6::RUNX1 Fusion - B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6::RUNX1 - B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) - B lymphoblastic leukemia/lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) - B-Lymphoblastic Leukemia/Lymphoma with ETV6-RUNX1 Fusion - B-Lymphoblastic Leukemia/Lymphoma with ETV6::RUNX1 Fusion - B-Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1)