Prothrombin

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Prothrombin (622 aa, ~70 kDa) is encoded by the human F2 gene. This protein plays a role in both coagulation and proteolysis of fibrinogen.

**Synonyms:** - Coagulation Factor II - EC 3.4.21.5 - F2 - Factor II