Sisomicin Sulfate

**Semantic type:** Antibiotic|Pharmacologic Substance

**Definition:** The sulfate salt form of sisomicin, a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is strucurally similar to gentamicin but has a unique unsaturated diamino sugar. Of the aminoglycoside antibiotics, sisomicin has the greatest activity against gram-positive bacteria.

**Synonyms:** - D-Streptamine, (2S-cis)-4-O-(3-Amino-6-(Aminomethyl)-3,4-Dihydro-2H-Pyran-2-yl)-2-Deoxy-6-O-(3-Deoxy-4-C-Methyl-3-(Methylamino)-Beta-L-Arabinopyranosyl)-, Sulfate (2:5) (Salt) - O-3-Deoxy-4-C-Methyl-3-(Methylamino)-Beta-L-Arabinopyranosyl-(1-4)-O-(2,6-Diamino-2,3,4,6-Tetradeoxy-Alpha-D-Glycero-Hex-4-Enopyranosyl-(1-6))-2-Deoxy-L-Streptamine Sulfate (2:5) (Salt) - SCH 13475 Sulfate - SISOMICIN SULFATE