Aminoglycoside Antibiotic

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any antibiotic containing amino-modified sugars originally isolated from various Streptomyces and Micromonospora species. Aminoglycoside antibiotics bind to the 16S RNA of the bacterial 30S ribosomal subunit, inhibiting translation and protein synthesis. Aminoglycoside use is associated with ototoxicity, neurotxicity and nephrotoxicity.

**Synonyms:** - Aminoglycoside Agents - Aminoglycoside Drugs - Aminoglycosides - aminoglycoside antibiotic