Pseudoisocytidine

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic, pyrimidine C-5 nucleoside with antineoplastic activity. Pseudoisocytidine, after conversion into pseudoisocytidine triphosphate, is incorporated into DNA and RNA eventually halting tumor cell proliferation. Compared to 5-azacytidine and cytarabine, this agent shows enhanced stability and resistance to enzymatic deamination.

**Synonyms:** - 4(1H)-Pyrimidinone, 2-Amino-5-Beta-D-Ribofuranosyl- - 5-(Beta-D-Ribofuranosyl)Isocytosine - PSEUDOISOCYTIDINE - psi Icyd