GTF2H5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GTF2H5 wild-type allele is located in the vicinity of 6q25.3 and is approximately 22 kb in length. This allele, which encodes general transcription factor IIH subunit 5 protein, plays a role in the regulation of both RNA polymerase II-mediated transcription and nucleotide excision repair. Mutation of the gene is associated with trichothiodystrophy, complementation group A.

**Synonyms:** - C6orf175 - Chromosome 6 Open Reading Frame 175 Gene - DNA Repair Syndrome Trichothiodystrophy Group A Gene - FLJ30544 - General Transcription Factor IIH, Polypeptide 5 wt Allele - TFB5 - TFIIH Basal Transcription Factor Complex TTDA Subunit Gene - TFIIH Basal Transcription Factor Complex, TTDA Subunit Gene - TGF2H5 - TTD - TTD-A - TTDA - Transcription Factor IIH, 8-kD Subunit Gene - Trichothiodystrophy Gene - bA120J8.2