E3 Ubiquitin-Protein Ligase Parkin

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase parkin (465 aa, ~52 kDa) is encoded by the human PRKN gene. This protein may play a role in the ubiquitination of proteins targeted for proteasomal degradation.

**Synonyms:** - EC 2.3.2.31 - EC 6.3.2.-, Formerly - PRKN - Parkin - Parkin RBR E3 Ubiquitin-Protein Ligase - Parkinson Disease Protein 2 - Parkinson Juvenile Disease Protein 2 - Parkinson Protein 2 E3 Ubiquitin Protein Ligase