Eg5 Kinesin-Related Motor Protein Inhibitor 4SC-205

**Semantic type:** Pharmacologic Substance

**Definition:** A small-molecule inhibitor of the human kinesin-related motor protein Eg5 with potential antineoplastic activity. Eg5 kinesin-related motor protein inhibitor 4SC-205 selectively inhibits the activity of Eg5, which may result in mitotic disruption, apoptosis and cell death. The ATP-dependent Eg5 kinesin-related motor protein (also known as KIF11 or kinesin spindle protein-5) is a plus-end directed kinesin motor protein essential for the regulation of spindle dynamics, including assembly and maintenance, during mitosis.

**Synonyms:** - 4SC 205 - 4SC-205 - 4SC205 - Eg5 Kinesin Inhibitor 4SC-205 - SC-205