Piritrexim Isethionate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The isethionate salt of piritrexim, a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.

**Synonyms:** - 2,4-Diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido(2,3-d)pyrimidine mono(2-hydroxyethanesulfonate) - BW-301U Isethionate - PIRITREXIM ISETHIONATE - Piritrexim isethionate