Pappalysin-1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Pappalysin-1 (1627 aa, ~181 kDa) is encoded by the human PAPPA gene. This protein is involved in the modulation of proteolysis.

**Synonyms:** - EC 3.4.24.79 - IGF-Dependent IGFBP-4 Protease - IGFBP-4ase - Insulin-Like Growth Factor-Dependent IGF-Binding Protein 4 Protease - PAPP-A - PAPPA - Pregnancy-Associated Plasma Protein A