Valinomycin

**Semantic type:** Amino Acid, Peptide, or Protein|Antibiotic|Pharmacologic Substance

**Definition:** A cyclic depsipeptide isolated from the bacterium Streptomyces fulvissimus. As a potassium-specific ionophore, mould element causes loss of mitochondrial membrane potential, thereby initiating cellular apoptosis. (NCI04)

**Synonyms:** - Antibiotic N-329 B - Cyclic(D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl) - Cyclododecadepespipeptide Neutral Ionophore - Mould Element - VALINOMYCIN - VALINOMYCIN