Pancreatic Glucagonoma

**Semantic type:** Neoplastic Process

**Definition:** A usually malignant, glucagon-producing neuroendocrine tumor arising from the pancreatic alpha cells. It may be associated with necrolytic erythema migrans, diarrhea, diabetes, glossitis, weight loss, malabsorption, and anemia. Almost 25% of patients experience thromboembolic complications, and 50% have liver metastases at the time of diagnosis.

**Synonyms:** - Glucagonoma - glucagonoma