Plocabulin

**Semantic type:** Pharmacologic Substance

**Definition:** A marine-derived, synthetically produced compound with potential antineoplastic activity. Plocabulin covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.

**Synonyms:** - PLOCABULIN - PM-060184 - PM060184